CHEMICOMECHANICAL CARIES REMOVAL (CARISOLV)

CARIDEX

The chemo-mechanical system for caries removal was published in 1975 by HABIB et al.

It is marketed under the trade name of Caridex.

Chemo-mechanical caries removal uses sodium hypochlorite (NaOCl), a non-specific proteolytic
agent (monoaminobutyric acid) removing organic components at room temperature


CARISOLV

Carisolv consists of a red gel and transperant fluid.

composition

Red gel
glutamic acid,
leucin,
lysine,
sodium chloride,
erythrosine,
water and sodium hydroxide

Transparent fluid
0.5% sodium hypochlorite


The chemical action of Carisolv is similar to that of Caridex in softening the carious dentin but leaving the healthy dentin unaffected

In caridex it was shown that, NaOCl was dissolving not only necrotic tissue but also sound dentin.

INSTRUMENTS
Special instruments designed to scrape in two or in several directions, which reduce the friction during caries excavation

MECHANISM OF ACTION

While mixing amino acids react with sodium hypochloride and forms chloromines.

chloromines seems to involve the chlorination of partially degraded collagen and the conversion of hydroxyproline to pyrrole-2-carboxylic acid, which initiates disruption of altered collagen fibres in carious dentin .